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Expired allergy injections - harmful?August 5, 2004
As allergy extract (sometimes referred to as allergy serum) ages, it becomes less potent. The more dilute the extract is, the sooner it will lose it's potency. When a concentrated extract is diluted, the preservative in the concentrate is also being diluted. Sometimes a small amount of preservative, such as glycerine, is added back to the diluted extract to help it last longer. In addition, storage of the allergy extract affects potency. Allergy extract should be refrigerated between shots or it may lose it's potency long before the expiration date on the bottle. The most likely consequence of using an expired extract, or one that has not been refrigerated, is not that it will cause a harmful reaction. It is that it will no longer be as effective. If your allergy extract is expired, there is more danger of an allergy reaction when a new vial is prepared. A new vial of extract is usually started at a lower dose because it is likely to be a little stronger. But if the old vial has been expired for some time, your allergist may decrease the starting dose of the new vial even more. References:
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