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Why do some people have allergies and some don't?

June 15, 2004

Dear Allergy Nurse
Dear Allergy Nurse
Why do some people have allergies and some people don't? Does it have to do with the immune system? Can you please explain it to me. -- M.L., California

Yes, it does involve the immune system. But, the most important reason some people develop allergies and some don't is thought to be heredity. Preventing exposure in early life seems to decrease the risk of allergies. However new research indicates that exposure to dogs in early life seems to enhance the development of the immune system, thus decreasing the risk the child will develop allergies.

People sometimes tell me they never had allergy symptoms until they moved to a new area. Moving to a new area may seem to trigger the immune response, but authorities believe these people already had hereditary tendency toward allergies.

The role of the immune system involves production of IgE which is sometimes called 'the allergic antibody.' This is fascinating to study. In June of last year I was asked by our sponsor National Allergy Supply to write a three part series about allergies and the immune system. I shared the role of the immune system in detail in the first two parts of the series. See:
'Why I Have Allergies' and 'Why They Make Me Sick'.



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References:

  1. Keeping your kids allergy and asthma free, American Academy of Allergy Asthma & Immunology (AAAAI).
  2. Protection against allergic disease linked to early dog exposure; early fever, from the Journal of Allergy and Clinical Immunology, American Academy of Allergy Asthma & Immunology (AAAAI).
  3. Tips to Remember: What is an Allergic Reaction?, American Academy of Allergy Asthma & Immunology (AAAAI).


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