Also, how long after you get your shot are you in the clear for a serious reaction? -- C.V., Virginia

If you are experiencing these symptoms before your shot, of course they are not a direct reaction from the shot. However, anytime you have symptoms of chest tightness or a strange feeling in your throat after an allergy injection, you need to seek medical help immediately.

Tightness in your chest and throat can indicate a systemic reaction to the shot. Your physician can help you determine if the reaction is a physical response to the shots, or anxiety about the shots.

Most people become less anxious about the injections after they have been getting them for awhile. If your anxiety only occurs in relation to the allergy shots, an anti-anxiety medication may not be the best choice. Try to stop thinking about the shots by focusing on a relaxing activity that you enjoy when thoughts of the shots come to mind.

When allergy shots are given according to correct medical protocol, serious reactions are actually quite rare. The most likely time for a serious reaction to an allergy shot is during the first 20 minutes after the shot. We require everyone to wait in our office at least 20 minutes after their injection. Some offices require a 30 minute wait. A systemic reaction to an allergy injection can occur up to 24 hours after the injection, especially if you are exposed to the things you are allergic to more than usual during that time.

Most of these reactions are not severe, though. The most common systemic reactions we see are an increase in symptoms of sneezing, runny nose, or watery eyes. In our clinic, we advise patients with increase in these symptoms after shots to be sure to take their antihistamine before they get their injections.

If more serious reactions occur, it's usually during the first two hours after the shot, but we have had patients report serious reactions three or four hours after a shot. Seek medical help immediately if you experience unusual symptoms after your allergy injection.

Always discuss anything you think may be a reaction to your allergy shot with your allergist or his nurse. They can help you determine the best course to take, and adjust your dose if needed.

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