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Treatment for angioedema (angioneurotic edema), swelling

October 28, 2003

Dear Allergy Nurse
Dear Allergy Nurse
My mother is suffering from extreme allergic reaction. Her body parts get swollen: patches on arms, legs and face, lips and eyes. It lasts for several days, but now the swelling is getting down from mouth to throat. Initially doctors suggested food allergies but have not alienated any specific food. Now it is getting very severe even after she has given up lots of food types. Can you suggest some test that can alienate the food that causes it. Is it a food allergy? or What else can be the cause of this severe reaction and what can we do to cure it. -- Soni, India

This sounds like angioedema. Angioedema is very dangerous, especially when it starts affecting the neck and throat. She should seek emergency medical help when she experiences swelling near her throat, as this can quickly impair breathing. Her physician may also be able to provide emergency epinephrine to be self-administered by injection during a life-threatening attack.

Angioedema is sometimes preceded by hives. Often the cause for hives and angioedema cannot be found. Likewise it is difficult to predict when an onslaught will occur, how long it will last, or whether this is something that will eventually subside.

However, I recently participated in a continuing educational course that offered hope. Dr. Michael Kaliner, Medical Director for the Institute for Asthma and allergy in Chevy Chase, Maryland, and a Clinical Professor of Medicine at George Washington School of Medicine in Washington, DC, says that he has successfully treated a good number of patients with angioedema by using a combination of antihistamines and antileukotrienes. You could talk to your physician about the possibility of trying antileukotriene medication. I have listed information about Dr. Kaliner's presentation in the references.



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References:

  1. Urticaria and Angioedema: New Directions for a New Century Dr. Michael Kaliner, Medical Director for the Institute for Asthma and allergy in Chevy Chase, Maryland, and a Clinical Professor of Medicine at George Washington School of Medicine in Washington, DC, Family Practice Update.
  2. Angioedema MEDLINEplus Health Information, National Institutes of Health, U.S. Government.


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